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U.S. Department of Health and Human Services Office of Disease Prevention and Health Promotion

Baclofen for Alcohol Withdrawal

About this resource:

Systematic Review

Source: The Cochrane Collaborative

Last Reviewed: August 2017

Workgroups: Substance Use Workgroup

In this Cochrane systematic review, the Cochrane Collaborative found that there’s not enough high-quality evidence to determine whether baclofen improves symptoms in people with alcohol withdrawal syndrome. The studies included in the review compared baclofen with placebo or another medicine. Researchers concluded that well‐designed double-blind randomized controlled trials with large numbers of participants are needed to test the effectiveness of baclofen.

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Objectives related to this resource (1)

Reduce the proportion of people who had alcohol use disorder in the past year — SU‑13
Little or no detectable change

Suggested Citation

1.

Liu, J. & Wang, L.N. (2017). Baclofen for alcohol withdrawal. Cochrane Database of Systematic Reviews, 2017 (8). DOI: 10.1002/14651858.CD008502.pub5.